departure Definition

1. An act of going away or leaving.

Thesaurus: leaving, going, departing, withdrawal, passage, exit, exodus, leave-taking, getaway (slang); Antonym: arrival.
2. A change from a planned or usual course of action.

Thesaurus: deviation, variation, change, divergence, branching out, difference, novelty, innovation.
Form: departure from something (often)
3. A new activity, different from what one has been doing or normally does.

Form: new departure (often)
4. naut.
The distance in nautical miles travelled by a ship due East or West.