unfortunate Definition

1. Unlucky; suffering misfortune or ill-luck.

Thesaurus: unlucky, doomed, ill-fated, star-crossed.
2. Resulting from or constituting bad luck.

Example: an unfortunate injury
3. Regrettable.

Thesaurus: regrettable, adverse, unfavourable, untimely, disastrous, calamitous, lamentable; Antonym: felicitous, promising.

1. An unfortunate person.

In an unfortunate way; unluckily.
Thesaurus: grievously, accidentally, perversely, calamitously.

It's unfortunate that ...; I'm sorry to say ....
Example: Unfortunately he can't come
Thesaurus: sadly, sad to say, regrettably.